Methylamine → HCID 178484399、化合物

反応式

[NH2:1][CH2:2][CH2:3][S:4][CH2:5][CH2:6][C:7]1[N:8]=[CH:9][NH:10][CH:11]=1.[N+](C=C(SC)SC)([O-])=O.[N+:21]([CH:24]=[C:25](SC)[NH:26][CH2:27]CSCCC1N=CNC=1)([O-:23])=[O:22].CN>>[N+:21]([CH:24]=[C:25]([NH:26][CH3:27])[NH:1][CH2:2][CH2:3][S:4][CH2:5][CH2:6][C:7]1[N:8]=[CH:9][NH:10][CH:11]=1)([O-:23])=[O:22]

参加物

反応物 4

HCID 6329Methylamine

HCID 836231,1-Bis(methylthio)-2-nitroethylene

HCID 178503827HCID 178503827、化合物

HCID 178511474HCID 178511474、化合物

生成物 1

HCID 178484399HCID 178484399、化合物

実験手順

4-[2-(2-Aminoethylthio)ethyl]imidazole (from the dihydrobromide (4.0 g)) isreacted with 1-nitro-2,2-bis-methylthioethylene (2.0 g) by the procedure ofExample 8(i) and the resultant 1-nitro-2-methylthio-2-[2-(2-(4-imidazolyl)ethylthio)ethylamino]ethylene is treated with methylamine according to the procedure of Example 8(ii) toyield the title compound.

出典と根拠

ORDレコード: ord-6ca0690722e1474093d2e609174c6c11
出典データセット: uspto-grants-1981_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04277485

反応ノート

読み込み中…