反応式
[I:1]I.[OH:3][CH2:4][C:5]1[S:6][CH:7]=[CH:8][C:9]=1[CH3:10]>C1C=CC=CC=1>[OH:3][CH2:4][C:5]1[S:6][C:7]([I:1])=[CH:8][C:9]=1[CH3:10]参加物
4
実験手順
6.58 G. (33 mmol) of mercuric oxide and 7.62 g. (30 mmol) of iodine were added alternately in small amounts to a vigorously stirred solution of 3.84 g. (30 mmol) of 2-hydroxymethyl-3-methylthiophene in 30 ml. of benzene. The reaction was kept at room temperature by cooling with an ice bath. The orange mercuric iodide which precipitated was filtered and washed well with benzene. The combined organic solutions were washed with sodium thiosulfate and saturated sodium chloride solution, dried and evaporated to yield crude 2-hydroxymethyl-3-methyl-5-iodothiophene as a colorless oil.
後処理
- customwas kept at room temperature
- temperatureby cooling with an ice bath
- customThe orange mercuric iodide which precipitated
- filtrationwas filtered
- washwashed well with benzene
- washThe combined organic solutions were washed with sodium thiosulfate and saturated sodium chloride solution
- customdried
- customevaporated
出典と根拠
- ORDレコード
- ord-8f91c11da0aa4924b866efa4a5fe7acc
- 出典データセット
- uspto-grants-1981_03
- 特許番号
- US04256878
関連ノート
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