2,2-Dimethoxyethylmethylamine → N-[4-(4-nitrophenoxy)-3-nitrophenyl]-N'-(2,2-dimethoxyethyl)-N'-methylurea

HRID 1277844ノート

反応式

HRID 1277844 の反応式
[N+:1]([C:4]1[CH:25]=[CH:24][C:7]([O:8][C:9]2[CH:14]=[CH:13][C:12]([NH:15][C:16](=[O:20])OCC)=[CH:11][C:10]=2[N+:21]([O-:23])=[O:22])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:26][O:27][CH:28]([O:32][CH3:33])[CH2:29][NH:30][CH3:31]>C1(C)C=CC=CC=1>[N+:1]([C:4]1[CH:25]=[CH:24][C:7]([O:8][C:9]2[CH:14]=[CH:13][C:12]([NH:15][C:16]([N:30]([CH2:29][CH:28]([O:32][CH3:33])[O:27][CH3:26])[CH3:31])=[O:20])=[CH:11][C:10]=2[N+:21]([O-:23])=[O:22])=[CH:6][CH:5]=1)([O-:3])=[O:2]

参加物

4

反応物 2

HCID 85032,2-DimethoxyethylmethylamineHCID 53855470Ethyl [4-(4-nitrophenoxy)-3-nitrophenyl]carbamate

生成物 1

HCID 23451783N-[4-(4-nitrophenoxy)-3-nitrophenyl]-N'-(2,2-dimethoxyethyl)-N'-methylurea

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

Ethyl [4-(4-nitrophenoxy)-3-nitrophenyl]carbamate (0.1 mole) and toluene (100 ml) are charged into a glass reaction vessel fitted with a mechanical stirrer, thermometer and condenser. N-(2,2-dimethoxyethyl)methanamine (0.15 mole) is added to the vessel and the mixture is refluxed for 16 hours. Solvent is then removed by mild warming under reduced pressure to yield the desired product N-[4-(4-nitrophenoxy)-3-nitrophenyl]-N'-(2,2-dimethoxyethyl)-N'-methylurea.

後処理

  1. customfitted with a mechanical stirrer
  2. temperaturethe mixture is refluxed for 16 hours
  3. customSolvent is then removed
  4. temperatureby mild warming under reduced pressure

出典と根拠

ORDレコード
ord-e37ae63485aa45368a49ec3f1f025f91
出典データセット
uspto-grants-1981_07
特許番号
US04279637

反応ノート

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