Hydrochloric Acid → HCID 23451744、化合物

HRID 1277845ノート

反応式

HRID 1277845 の反応式
[N+](C1C=CC(O[C:9]2[CH:14]=[CH:13][C:12]([NH:15][C:16]([N:18]([CH2:20][CH:21](OC)OC)[CH3:19])=[O:17])=[CH:11][C:10]=2[N+:26]([O-:28])=[O:27])=CC=1)([O-])=O.Cl.[OH2:32]>>[CH3:19][N:18]1[CH:20]=[CH:21][N:15]([C:12]2[CH:13]=[CH:14][C:9]([O:32][C:13]3[CH:12]=[CH:11][C:10]([N+:26]([O-:28])=[O:27])=[CH:9][CH:14]=3)=[C:10]([N+:26]([O-:28])=[O:27])[CH:11]=2)[C:16]1=[O:17]

参加物

4

反応物 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 23451783N-[4-(4-nitrophenoxy)-3-nitrophenyl]-N'-(2,2-dimethoxyethyl)-N'-methylurea

生成物 1

HCID 23451744HCID 23451744、化合物

実験手順

N-[4-(4-Nitrophenoxy)-3-nitrophenyl]-N'-(2,2-dimethoxyethyl)-N'-methylurea (0.02 mole), water (30 ml) and concentrated hydrochloric acid (3 ml) are charged into a glass reaction vessel fitted with a mechanical stirrer, thermometer and condenser. The mixture is refluxed for a period of about 30 minutes then cooled and extracted with ethyl acetate. The extract is washed with dilute aqueous sodium bicarbonate, with two portions of water and is then dried. The ethyl acetate is removed by mild warming under reduced pressure to yield the desired product 1-methyl-3-[4-(4-nitrophenoxy)-3-nitrophenyl]-4-imidazolin-2-one.

後処理

  1. customfitted with a mechanical stirrer
  2. temperatureThe mixture is refluxed for a period of about 30 minutes
  3. temperaturethen cooled
  4. extractionextracted with ethyl acetate
  5. washThe extract is washed with dilute aqueous sodium bicarbonate, with two portions of water
  6. customis then dried
  7. customThe ethyl acetate is removed
  8. temperatureby mild warming under reduced pressure

出典と根拠

ORDレコード
ord-00e9460ac25348989c07802ae42f0340
出典データセット
uspto-grants-1981_07
特許番号
US04279637

反応ノート

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