HCID 54437636、化合物 → 2-(alpha-Cyano-4-aminobenzylidene)-1-methylpyrrolidine

HRID 1278076

反応式

HRID 1278076 の反応式
[C:1]([C:3](=[C:13]1[CH2:17][CH2:16][CH2:15][N:14]1[CH3:18])[C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-])=O)=[CH:6][CH:5]=1)#[N:2]>C(O)C.[Pt].[H][H]>[C:1]([C:3](=[C:13]1[CH2:17][CH2:16][CH2:15][N:14]1[CH3:18])[C:4]1[CH:5]=[CH:6][C:7]([NH2:10])=[CH:8][CH:9]=1)#[N:2]

参加物

4

反応物 1

HCID 54437636HCID 54437636、化合物

生成物 1

HCID 536441372-(alpha-Cyano-4-aminobenzylidene)-1-methylpyrrolidine収率 62.7%

試薬・触媒・溶媒 2

HCID 178506450HCID 178506450、化合物触媒HCID 702Ethanol溶媒

実験手順

Dissolve 10 g of 2-(α-cyano-4-nitrobenzylidene)-1-methylpyrrolidine in ethanol and then reduce it with platinum/hydrogen. After completion of hydrogen uptake, filter the catalyst from the hydrogenated product, distil off the solvent and recrystallize the residue from 50 ml of ethanol to obtain 5.5 g of the title compound as light-brown crystals of m.p. 116° to 118°.

後処理

  1. filtrationAfter completion of hydrogen uptake, filter the catalyst from the hydrogenated product
  2. customdistil off the solvent
  3. customrecrystallize the residue from 50 ml of ethanol

出典と根拠

ORDレコード
ord-786f24fc0cf540cf8ca0fc790dc9bf58
出典データセット
uspto-grants-1981_07
特許番号
US04279918

関連ノート

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