Methyl diethylphosphonoacetate → (E)-1-(7-methoxycarbonyl-5,5-dimethyl-6-heptenyl)imidazole

反応式

[CH:1]([C:3]([CH3:14])([CH3:13])[CH2:4][CH2:5][CH2:6][CH2:7][N:8]1[CH:12]=[CH:11][N:10]=[CH:9]1)=O.[CH3:15][O:16][C:17]([CH2:19]P(=O)(OCC)OCC)=[O:18]>>[CH3:15][O:16][C:17](/[CH:19]=[CH:1]/[C:3]([CH3:14])([CH3:13])[CH2:4][CH2:5][CH2:6][CH2:7][N:8]1[CH:12]=[CH:11][N:10]=[CH:9]1)=[O:18]

参加物

反応物 2

HCID 66113Methyl diethylphosphonoacetate

HCID 128704761-(5-Formyl-5-methylhexyl)imidazole

生成物 1

HCID 20521646(E)-1-(7-methoxycarbonyl-5,5-dimethyl-6-heptenyl)imidazole

実験手順

By the proceeding as described in Example 1 but utilizing 1-(5-formyl-5-methylhexyl)imidazole and diethyl methoxycarbonylmethylphosphonate, there was obtained the title compound having the following physical characteristic in 66% yields:

出典と根拠

ORDレコード: ord-f24b70a2db844605b4cdbc555fb9c976
出典データセット: uspto-grants-1981_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04256757

反応ノート

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