関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Formanilide | HCID 7671 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 2-Chloro-5-nitrobenzotrifluoride | HCID 61213 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 4-Nitrodiphenylamine | HCID 13271 | — |
反応手順
the formanilide is treated with a one-molar equivalent of sodium hydride in dimethylformamide and the resulting solution of the sodium salt is treated with 2-chloro-5-nitrobenzotrifluoride (U.S. Pat. No. 3,657,350) at an elevated temperature (e.g., 155° C., reflux), to give the 4-nitrodiphenylamine (J. Organic Chemistry, 42, 1786 (1977) and references therein).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04257805 |
|---|
| 出典データセット | uspto-grants-1981_03 |
|---|
| ORD ID | ord-637345e1568f43cdb0c527fe3b2389c2 |
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| 出典メモ | uspto-grants-1981_03 |
|---|
