2-Amino-5-chloropyridine → Benzamide, 2-chloro-N-(((5-chloro-2-pyridinyl)amino)carbonyl)-6-fluoro-

HRID 1278184ノート

反応式

HRID 1278184 の反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH2:8])=[N:6][CH:7]=1.[Cl:9][C:10]1[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[C:11]=1[C:12]([NH:14][C:15](Cl)=[O:16])=[O:13]>>[Cl:9][C:10]1[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[C:11]=1[C:12]([NH:14][C:15]([NH:8][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][N:6]=1)=[O:16])=[O:13]

参加物

3

反応物 2

HCID 661742-Amino-5-chloropyridineHCID 537976672-Chloro-6-fluorobenzamidocarboxylic acid chloride

生成物 1

HCID 174171Benzamide, 2-chloro-N-(((5-chloro-2-pyridinyl)amino)carbonyl)-6-fluoro-

実験手順

A portion of 5-chloro-2-aminopyridine is reacted with 2-chloro-6-fluorobenzamidocarboxylic acid chloride in the presence of a hydrogen halide acceptor as described in Example 12. The product, named in the heading above, is isolated as described in Example 12 to obtain the desired compound, identical to the product of Example 3.

後処理

  1. customis isolated

出典と根拠

ORDレコード
ord-0cf6ec76afe74b3dbc3b15707b9e3905
出典データセット
uspto-grants-1981_07
特許番号
US04281003

反応ノート

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