Pyrazole, 3-amino-4-cyano-5-ethyl- → 2-Ethyl-7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
反応式
[NH2:1][C:2]1[C:6]([C:7]#[N:8])=[C:5]([CH2:9][CH3:10])[NH:4][N:3]=1.CN(C)[CH:13]=[CH:14][C:15]([C:17]1[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=1)=O>C(O)(=O)C>[CH2:9]([C:5]1[C:6]([C:7]#[N:8])=[C:2]2[N:1]=[CH:13][CH:14]=[C:15]([C:17]3[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=3)[N:3]2[N:4]=1)[CH3:10]参加物
4
実験手順
As for Example 2, 2.72 g. of 3-amino-5-ethylpyrazole-4-carbonitrile is heated at reflux temperature for 16 hours with 3.52 g. of 3-dimethylamino-1-(3-pyridyl)-2-propen-1-one in 25 ml. of glacial acetic acid to give 2.65 g. of the product of the example as colorless crystals, m.p. 170°-172° C.
後処理
- temperatureat reflux temperature for 16 hours with 3.52 g
出典と根拠
- ORDレコード
- ord-7717df1e1ad04ec592ca9a30f3d9a2e4
- 出典データセット
- uspto-grants-1981_07
- 特許番号
- US04281000
反応ノート
読み込み中…