2-Acetylpyridine → 3-Dimethylamino-1-(2-pyridyl)prop-2-en-1-one

HRID 1278244

反応式

HRID 1278244 の反応式
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1)(=[O:3])[CH3:2].CO[CH:12](OC)[N:13]([CH3:15])[CH3:14]>>[CH3:12][N:13]([CH3:15])[CH:14]=[CH:2][C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1)=[O:3]

参加物

3

反応物 2

HCID 142862-AcetylpyridineHCID 78373Dimethylformamide dimethyl acetal

生成物 1

HCID 5669933-Dimethylamino-1-(2-pyridyl)prop-2-en-1-one

実験手順

A mixture of 25 g. of 2-acetylpyridine and 35 ml. of N,N-dimethylformamide dimethylacetal is refluxed for 16 hours. The mixture is cooled and filtered to give 3-dimethylamino-1-(2-pyridyl)-2-propen-1-one as crystals, m.p. 127°-130° C.

後処理

  1. additionA mixture of 25 g
  2. temperatureThe mixture is cooled
  3. filtrationfiltered

出典と根拠

ORDレコード
ord-fba50ffebeec490ab54d32fcab05d345
出典データセット
uspto-grants-1981_07
特許番号
US04281000

関連ノート

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