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llms.txt · MCPガイドプライバシーポリシー · 利用規約 · サポートv1.8.0
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Hydrochloric Acid → 2,4-Imidazolidinedione, 5-(4-methoxy-3-methylphenyl)-5-(4-methoxyphenyl)-

HRID 1278255
ノート
印刷プレビュー

反応式

HRID 1278255 の反応式
[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([C:7]([C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][CH:10]=2)=O)=[CH:5][C:4]=1[CH3:19].[C-]#[N:21].[K+].[C:23](=[O:26])([O-])O.[NH4+].[CH:28]([NH2:30])=[O:29].Cl>O>[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([C:7]2([C:9]3[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][CH:10]=3)[NH:21][C:28](=[O:29])[NH:30][C:23]2=[O:26])=[CH:5][C:4]=1[CH3:19]
参加物実験手順後処理出典と根拠反応ノート

参加物

7

反応物 5

HCID 313Hydrochloric AcidHCID 713FormamideHCID 9032Potassium CyanideHCID 14013Ammonium BicarbonateHCID 19864229HCID 19864229、化合物

生成物 1

HCID 30581982,4-Imidazolidinedione, 5-(4-methoxy-3-methylphenyl)-5-(4-methoxyphenyl)-

試薬・触媒・溶媒 1

HCID 962
Water
溶媒
2 回

実験手順

34.5 Grams of 4,4'-dimethoxy-3-methylbenzophenone, 66.7 g of potassium cyanide and 232.2 g of ammonium hydrogencarbonate were heated to 120° C. together with 500 ml. of formamide and 100 ml. of water with stirring in an autoclave. After 72 hours, the reaction liquid was made acidic with concentrated hydrochloric acid, mixed with water and allowed to stand overnight. The precipitates thus formed were filtered out. The precipitates were dissolved in acetone, decolorized by active carbon under heating and recrystallized from hexane-acetone to obtain 22.7 g of 5-(4-methoxy-3-methylphenyl)-5-(4-methoxyphenyl)-hydantoin in the form of white crystals.

後処理

  1. customthe reaction liquid
  2. waitto stand overnight
  3. customThe precipitates thus
  4. customformed
  5. filtrationwere filtered out
  6. dissolutionThe precipitates were dissolved in acetone
  7. temperatureunder heating
  8. customrecrystallized from hexane-acetone

出典と根拠

ORDレコード
ord-676d664ae2ee41bc83bcef77a20d934f
出典データセット
uspto-grants-1981_07
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US04281009

反応ノート

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