2,4-Imidazolidinedione, 5,5-bis(2-(phenylmethoxy)phenyl)- → 2,4-Imidazolidinedione, 5,5-bis(2-hydroxyphenyl)-

HRID 1278257ノート

反応式

HRID 1278257 の反応式
C([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15]1([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[O:28]CC2C=CC=CC=2)[NH:19][C:18](=[O:20])[NH:17][C:16]1=[O:21])C1C=CC=CC=1>[C].[Pd].O1CCOCC1>[OH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15]1([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[OH:28])[NH:19][C:18](=[O:20])[NH:17][C:16]1=[O:21]

参加物

4

反応物 1

HCID 30582032,4-Imidazolidinedione, 5,5-bis(2-(phenylmethoxy)phenyl)-

生成物 1

HCID 30582122,4-Imidazolidinedione, 5,5-bis(2-hydroxyphenyl)-

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 312751,4-Dioxane溶媒

反応条件

温度
80 °C

実験手順

11.0 Grams of 5,5-bis(2-benzyloxyphenyl)hydantoin (Example 12) were reduced in 150 ml. of dioxane in the presence of 2 g of palladium-carbon catalyst in an autoclave under a hydrogen pressure of 10 Kg/cm2 at room temperature. After completion of the hydrogen absorption, the whole was heated at 80° C. under a hydrogen pressure of 10 Kg/cm2 for about 5 hours. The reaction liquid was subjected to filtration to remove the catalyst and concentrated under reduced pressure and the resulting precipitates were filtered out. The product was recrystallized from a mixture of acetone-chloroform to obtain 3.4 g of 5,5-bis(2-hydroxyphenyl)hydantoin in the form of white crystals.

後処理

  1. customat room temperature
  2. customAfter completion of the hydrogen absorption
  3. customThe reaction liquid
  4. filtrationwas subjected to filtration
  5. customto remove the catalyst
  6. concentrationconcentrated under reduced pressure
  7. customthe resulting precipitates
  8. filtrationwere filtered out
  9. customThe product was recrystallized from a mixture of acetone-chloroform

出典と根拠

ORDレコード
ord-8934dc9f3cb74bf8bd79a9af0a003ed8
出典データセット
uspto-grants-1981_07
特許番号
US04281009

反応ノート

読み込み中…