HCID 12565692、化合物 → 5-Indanacetic acid, 3-oxo-
反応式
[C:1]([CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][C:13]([OH:15])=[O:14])=[CH:8][CH:7]=1)([OH:3])=O>O>[O:3]=[C:1]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([CH2:12][C:13]([OH:15])=[O:14])[CH:10]=2)[CH2:5][CH2:4]1参加物
3
実験手順
Polyphosphoric acid (1 kg) was stirred and heated to 95°-100° C. and 4-(2-Carboxyethyl)phenylacetic acid (100 g, 0.48 mol) added over 10 minutes. The mixture was stirred for 0.5 hours and poured into ice and H2O; the product was continuously extracted with CHCl3, and recrystallised from benzene to give the title product, m.p. 133°-5° C.
後処理
- temperatureheated to 95°-100° C.
- extractionthe product was continuously extracted with CHCl3
- customrecrystallised from benzene
出典と根拠
- ORDレコード
- ord-990dcfcc3ee74ee2b7de5d13a7a17531
- 出典データセット
- uspto-grants-1981_07
- 特許番号
- US04281017
反応ノート
読み込み中…