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Sulfuric acid magnesium salt (1:1) → Methyl (2E)-{[(2,4-dimethoxyphenyl)methyl]imino}acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| 反応物 | Acetic acid, 2-oxo-, methyl ester | HCID 70205 | — |
| 反応物 | 2,4-Dimethoxybenzylamine | HCID 597250 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Methyl (2E)-{[(2,4-dimethoxyphenyl)methyl]imino}acetate | HCID 23470137 | — |
反応手順
To a mixture containing 16.82 g (0.101 mole) of 2,4-dimethoxybenzylamine and anhydrous magnesium sulfate in 150 ml of methylene chloride at 25° is added a solution of 10.05 g (0.114 mole) of methyl glyoxalate in 20 ml of methylene chloride. The reaction mixture is stirred at room temperature overnight (15 hours) and then is filtered and the solvents are removed in vacuo to afford the imine as a dark orange gum.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04257947 |
| 出典データセット | uspto-grants-1981_03 |
| ORD ID | ord-3a6afd3455a641c0957d904292864f54 |
| 出典メモ | uspto-grants-1981_03 |