関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hexadecanolide | HCID 7984 | — |
| 反応物 | Sodium Thiosulfate | HCID 24477 | — |
| 反応物 | Hydrogen iodide | HCID 24841 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 16-Iodohexadecanoic acid | HCID 41111 | — |
反応手順
16-Hexadecanolide (5.0 g, 0.02 mol) was added to a mixture of HI (30 g) and acetic acid (20 g). The mixture was heated to 100° C. overnight. After cooling it was poured into a cold sodium thiosulphate solution (150 mL, 10%) and extracted using CH2Cl2. The combined organic extracts were dried (MgSO4) and evaporated to give a white solid. The crude product was recrystallised from diethyl ether. Yield: 4.8 g (64%)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06447656B1 |
|---|
| 出典データセット | uspto-grants-2002_09 |
|---|
| ORD ID | ord-5e69fe56e7e042fd9f6eb6361228f83f |
|---|
| 出典メモ | uspto-grants-2002_09 |
|---|
