Phenyl isocyanate → HCID 20432999、化合物

HRID 127989ノート

反応式

HRID 127989 の反応式
[C:1]1([N:7]=[C:8]=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:10]([N:28]([CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH3:56])[CH2:29][CH2:30][CH2:31][N:32]([CH2:36][CH2:37][OH:38])[CH2:33][CH2:34][OH:35])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>C(OC(=O)C)C>[CH2:39]([N:28]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH2:29][CH2:30][CH2:31][N:32]([CH2:33][CH2:34][O:35][C:8](=[O:9])[NH:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH2:36][CH2:37][O:38][C:8](=[O:9])[NH:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH3:56]

参加物

4

反応物 2

HCID 7672Phenyl isocyanateHCID 37186Avridine

生成物 1

HCID 20432999HCID 20432999、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

Phenyl isocyanate (3.85 g.) is added to a warm solution of N,N-dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-propanediamine (5.0 g.) in ethylacetate (20 ml.) and the mixture heated to reflux for one hour. The mixture is cooled, then taken to dryness under reduced pressure. The residue is triturated with carbon tetrachloride, filtered, and the filtrate evaporated to dryness. Ethyl acetate (25 ml.) is then added, the mixture cooled, filtered, washed with ethylacetate and dried in vacuo; m.p. 54°-6° C.

後処理

  1. temperaturethe mixture heated
  2. temperatureto reflux for one hour
  3. temperatureThe mixture is cooled
  4. customThe residue is triturated with carbon tetrachloride
  5. filtrationfiltered
  6. customthe filtrate evaporated to dryness
  7. additionEthyl acetate (25 ml.) is then added
  8. temperaturethe mixture cooled
  9. filtrationfiltered
  10. washwashed with ethylacetate
  11. customdried in vacuo

出典と根拠

ORDレコード
ord-6b00e276d3d44b24a160cb083abd3c07
出典データセット
uspto-grants-1981_03
特許番号
US04258061

反応ノート

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