Serinol → 5-Amino-3-acetoxymethyl-N-(1,3-dihydroxyprop-2-yl)-2,4,6-triiodobenzamide

HRID 1280162ノート

反応式

HRID 1280162 の反応式
[NH2:1][C:2]1[C:3]([I:18])=[C:4]([CH2:13][O:14][C:15](=[O:17])[CH3:16])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7](Cl)=[O:8].[NH2:19][CH:20]([CH2:23][OH:24])[CH2:21][OH:22]>>[NH2:1][C:2]1[C:3]([I:18])=[C:4]([CH2:13][O:14][C:15](=[O:17])[CH3:16])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7]([NH:19][CH:20]([CH2:23][OH:24])[CH2:21][OH:22])=[O:8]

参加物

3

反応物 2

HCID 68294SerinolHCID 184293385-Amino-3-acetoxymethyl-2,4,6-triiodobenzoyl chloride

生成物 1

HCID 184293075-Amino-3-acetoxymethyl-N-(1,3-dihydroxyprop-2-yl)-2,4,6-triiodobenzamide収率 95%

実験手順

5-Amino-3-acetoxymethyl-2,4,6-triiodobenzoyl chloride was reacted with serinol according to the conditions in Example 24g. The product was isolated in 95% yield.

後処理

  1. customThe product was isolated in 95% yield

出典と根拠

ORDレコード
ord-36570c1883544e0686c582f5d6e74d32
出典データセット
uspto-grants-2002_09
特許番号
US06448442B1

反応ノート

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