2,3,4,5-Tetrachloropyridine → Pyridine, 2,3,5-trichloro-

HRID 128056

反応式

HRID 128056 の反応式
[Cl:1][C:2]1[C:7]([Cl:8])=[C:6](Cl)[C:5]([Cl:10])=[CH:4][N:3]=1.COP(C)(=O)O>[Zn]>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([Cl:10])=[CH:4][N:3]=1

参加物

4

反応物 2

HCID 760512,3,4,5-TetrachloropyridineHCID 316552Monomethyl methylphosphonate

生成物 1

HCID 27666Pyridine, 2,3,5-trichloro-収率 76.7%

試薬・触媒・溶媒 1

HCID 23994Zinc触媒

実験手順

By the method described in Example 1, 11.0 g (0.05 mol) of 2,3,4,5-tetrachloropyridine, 4.4 g (0.065 gram atom) of zinc dust (96%) and 9.5 g (0.075 mol) of the ammonium salt of methanephosphonic acid monomethyl ester are reacted to obtain 7.0 g (76% of theory) of 2,3,5-trichloropyridine, m.p. 37°-40° C., which contains, according to gas-chromatographical analysis, 78.8% of 2,3,5-trichloropyridine, 2.5% of 2,3,4,5-tetrachloropyridine and 0.61% of unknown products.

後処理

  1. customare reacted

出典と根拠

ORDレコード
ord-f50452bfcca443a187655f2f5c207888
出典データセット
uspto-grants-1981_03
特許番号
US04258194

関連ノート

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