2-(Chloromethyl)naphthalene → 5,6-Dichloro2-(4-formylphenyl)-1-(2-naphtylmethyl)benzimidazole

HRID 1281129

反応式

HRID 1281129 の反応式
[Cl:1][C:2]1[C:18]([Cl:19])=[CH:17][C:5]2[N:6]=[C:7]([C:9]3[CH:14]=[CH:13][C:12]([CH:15]=[O:16])=[CH:11][CH:10]=3)[NH:8][C:4]=2[CH:3]=1.Cl[CH2:21][C:22]1[CH:31]=[CH:30][C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[CH:23]=1>>[Cl:19][C:18]1[C:2]([Cl:1])=[CH:3][C:4]2[N:8]([CH2:21][C:22]3[CH:31]=[CH:30][C:29]4[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=4)[CH:23]=3)[C:7]([C:9]3[CH:10]=[CH:11][C:12]([CH:15]=[O:16])=[CH:13][CH:14]=3)=[N:6][C:5]=2[CH:17]=1

参加物

3

反応物 2

HCID 756322-(Chloromethyl)naphthaleneHCID 184267935,6-Dichloro-2-(4-formylphenyl)benzimidazole

生成物 1

HCID 184268635,6-Dichloro2-(4-formylphenyl)-1-(2-naphtylmethyl)benzimidazole

実験手順

5,6-dichloro2-(4-formylphenyl)-1-(2-naphtylmethyl)benzimidazole was prepared from 5,6-dichloro-2-(4-formylphenyl)benzimidazole obtained in Example 13 and 2-chloromethylnaphthalene by following General Procedure 3.

出典と根拠

ORDレコード
ord-dc2519b26c0d4ebdb5ab6dd7308cd815
出典データセット
uspto-grants-2002_09
特許番号
US06452014B1

関連ノート

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