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1,1-Dibromoethane → 2-(2-Bromoethoxy)-1,3-dimethylbenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,1-Dibromoethane | HCID 11201 | — |
| 反応物 | 2,6-Dimethylphenol | HCID 11335 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-(2-Bromoethoxy)-1,3-dimethylbenzene | HCID 2452208 | — |
反応手順
To a solution containing sodium hydroxide (80 g) in water (1 liter) and ethanol (0.5 liter) are added 2,6-dimethyl-phenol (245 g) dissolved in ethanol (0.5 liter), and then dibromoethane (750 g). The mixture is refluxed for 48 hours, under vigorous stirring. It is then extracted with methylene chloride. After washing with dilute aqueous sodium hydroxide and then with water, the solvent is evaporated in vacuo. 2(2,6-Dimethyl-phenoxy)-1-bromo-ethane boils at 148°-150° C./25 mm Hg.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04259334 |
| 出典データセット | uspto-grants-1981_03 |
| ORD ID | ord-7b9296f09277488298a19d66a77727f6 |
| 出典メモ | uspto-grants-1981_03 |