Allyl isocyanate → 1-Allyl-3-butyl-3-(4-methyl-2-oxazolyl)urea

HRID 128232

反応式

HRID 128232 の反応式
[CH2:1]([NH:5][C:6]1[O:7][CH:8]=[C:9]([CH3:11])[N:10]=1)[CH2:2][CH2:3][CH3:4].[CH2:12]([N:15]=[C:16]=[O:17])[CH:13]=[CH2:14]>C1C=CC=CC=1>[CH2:12]([NH:15][C:16]([N:5]([CH2:1][CH2:2][CH2:3][CH3:4])[C:6]1[O:7][CH:8]=[C:9]([CH3:11])[N:10]=1)=[O:17])[CH:13]=[CH2:14]

参加物

4

反応物 2

HCID 15123Allyl isocyanateHCID 122952262-Oxazolamine, N-butyl-4-methyl-

生成物 1

HCID 234689701-Allyl-3-butyl-3-(4-methyl-2-oxazolyl)urea

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

A solution of 2-butylamino-4-methyloxazole (12.0 g, 0.078 mol) and allyl isocyanate (6.46 g, 0.078 mol) in dry benzene was heated under reflux for 4 hours, and worked up as described in Example 3. The product was further purified by chromatography on a silica-gel column, eluting with a 1:1 mixture of benzene and ethyl acetate.

後処理

  1. temperatureunder reflux for 4 hours
  2. customThe product was further purified by chromatography on a silica-gel column
  3. washeluting with a 1:1 mixture of benzene and ethyl acetate

出典と根拠

ORDレコード
ord-a818f0b90bf44e699db9a3fff5848ae3
出典データセット
uspto-grants-1981_03
特許番号
US04259343

関連ノート

読み込み中…