3,4,5,6-Tetrahydro-2H-cyclopenta(d)(1,3)thiazol-2-imine → N-(5,6-Dihydro-4H-cyclopentathiazole-2-yl)-4-hydroxy-2-methyl-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxide

HRID 128273

反応式

HRID 128273 の反応式
[OH:1][C:2]1[C:7]2[S:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:6]=2[S:5](=[O:16])(=[O:15])[N:4]([CH3:17])[C:3]=1[C:18](OC)=[O:19].[S:22]1[C:26]2[CH2:27][CH2:28][CH2:29][C:25]=2[N:24]=[C:23]1[NH2:30]>>[S:22]1[C:26]2[CH2:27][CH2:28][CH2:29][C:25]=2[N:24]=[C:23]1[NH:30][C:18]([C:3]1[N:4]([CH3:17])[S:5](=[O:15])(=[O:16])[C:6]2[C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=3[S:8][C:7]=2[C:2]=1[OH:1])=[O:19]

参加物

3

反応物 2

HCID 3322553,4,5,6-Tetrahydro-2H-cyclopenta(d)(1,3)thiazol-2-imineHCID 547072593-carbomethoxy-4-hydroxy-2-methyl-2H-[1]benzothieno[2,3-e]-1,2-thiazine 1,1-dioxide

生成物 1

HCID 86737639N-(5,6-Dihydro-4H-cyclopentathiazole-2-yl)-4-hydroxy-2-methyl-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxide収率 57%

実験手順

Prepared analogous to Example 1 from methyl 4-hydroxy-2-methyl-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and 5,6-dihydro-4H-cyclopentathiazole-2-amine with a yield of 57% of theory.

出典と根拠

ORDレコード
ord-0f2eb9fbd17e44598901f780fe921616
出典データセット
uspto-grants-1981_03
特許番号
US04259336

関連ノート

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