Olivetol → 1,2-dihydro-9-hydroxy-4-oxo-7-(pentyl)-4H-thieno[2,3-c] [1]benzopyran

反応式

O=[C:2]1[CH2:6][CH2:5][S:4][CH:3]1[C:7]([O:9][CH3:10])=[O:8].[CH2:11]([C:16]1[CH:17]=C(O)[CH:19]=[C:20]([CH:22]=1)[OH:21])[CH2:12][CH2:13][CH2:14][CH3:15]>>[OH:21][C:20]1[C:19]2[C:2]3[CH2:6][CH2:5][S:4][C:3]=3[C:7](=[O:8])[O:9][C:10]=2[CH:17]=[C:16]([CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[CH:22]=1

参加物

反応物 2

HCID 10377Olivetol

HCID 1028702-Thiophenecarboxylic acid, tetrahydro-3-oxo-, methyl ester

生成物 1

HCID 214339321,2-dihydro-9-hydroxy-4-oxo-7-(pentyl)-4H-thieno[2,3-c] [1]benzopyran

実験手順

Following a procedure similar to that described in Example 1B hereinabove, methyl 3-oxo-2,3,4,5-tetrahydrothiophene-2-carboxylate is reacted with 5-(1-pentyl)resorcinol to give 1,2-dihydro-9-hydroxy-4-oxo-7-(1-pentyl)-4H-thieno[2,3-c] [1]benzopyran.

出典と根拠

ORDレコード: ord-2766806890c94ac28f923b1ffaf3310e
出典データセット: uspto-grants-1976_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US03972880

反応ノート

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