2-Amino-3-Hydroxypyridine → 2,7-Dimethyl-4-hydroxy-N-(3-hydroxy-2pyridyl)-2H-[1]-benzothieno-[2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxide

HRID 128286

反応式

HRID 128286 の反応式
[CH3:1][N:2]1[C:7]([C:8](OC)=[O:9])=[C:6]([OH:12])[C:5]2[S:13][C:14]3[CH:19]=[C:18]([CH3:20])[CH:17]=[CH:16][C:15]=3[C:4]=2[S:3]1(=[O:22])=[O:21].[NH2:23][C:24]1[C:29]([OH:30])=[CH:28][CH:27]=[CH:26][N:25]=1>>[CH3:1][N:2]1[C:7]([C:8]([NH:23][C:24]2[C:29]([OH:30])=[CH:28][CH:27]=[CH:26][N:25]=2)=[O:9])=[C:6]([OH:12])[C:5]2[S:13][C:14]3[CH:19]=[C:18]([CH3:20])[CH:17]=[CH:16][C:15]=3[C:4]=2[S:3]1(=[O:22])=[O:21]

参加物

3

反応物 2

HCID 281142-Amino-3-HydroxypyridineHCID 70578267methyl 2,7-dimethyl-4-hydroxy-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide

生成物 1

HCID 705790822,7-Dimethyl-4-hydroxy-N-(3-hydroxy-2pyridyl)-2H-[1]-benzothieno-[2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxide収率 38%

実験手順

Prepared analogous to Example 1 from methyl 2,7-dimethyl-4-hydroxy-2H-[1]-benzothieno-[2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and 2-amino-3-hydroxy-pyridine with a yield of 38% of theory.

出典と根拠

ORDレコード
ord-1e200182c410436d83b80e49fe290b98
出典データセット
uspto-grants-1981_03
特許番号
US04259336

関連ノート

読み込み中…