p-Anisoyl chloride → 2-(4-Chlorophenyl)-3-(4-hydroxybenzoyl)benzofuran

HRID 1283654ノート

反応式

HRID 1283654 の反応式
ClC1C=CC(C2OC3C=CC=CC=3C=2)=CC=1.C(Cl)(=O)C1C=CC(OC)=CC=1.[Cl:28][C:29]1[CH:34]=[CH:33][C:32]([C:35]2[O:36][C:37]3[CH:53]=[CH:52][CH:51]=[CH:50][C:38]=3[C:39]=2[C:40](=[O:49])[C:41]2[CH:46]=[CH:45][C:44]([O:47]C)=[CH:43][CH:42]=2)=[CH:31][CH:30]=1.Cl.N1C=CC=CC=1>>[Cl:28][C:29]1[CH:34]=[CH:33][C:32]([C:35]2[O:36][C:37]3[CH:53]=[CH:52][CH:51]=[CH:50][C:38]=3[C:39]=2[C:40](=[O:49])[C:41]2[CH:46]=[CH:45][C:44]([OH:47])=[CH:43][CH:42]=2)=[CH:31][CH:30]=1

参加物

5

反応物 4

HCID 7477p-Anisoyl chlorideHCID 43683122-(4-Chlorophenyl)-1-benzofuranHCID 10176127Pyridinium chlorideHCID 214352602-(4-Chlorophenyl)-3-(4-methoxybenzoyl)benzofuran

生成物 1

HCID 214352692-(4-Chlorophenyl)-3-(4-hydroxybenzoyl)benzofuran

実験手順

When 2-(4'-chlorophenyl)benzofuran was acylated with anisoyl chloride was described in the procedure of Example 10 and the resulting 2-(4'-chlorophenyl)-3-(4'-methoxybenzoyl)benzofuran was demethylated with pyridine hydrochloride as previously described, 2-(4'-chlorophenyl)-3-(4'-hydroxybenzoyl)benzofuran was obtained.

出典と根拠

ORDレコード
ord-bb0180e88aad4302bb8aea0542a7b9d2
出典データセット
uspto-grants-1976_08
特許番号
US03975537

反応ノート

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