Hydrochloric Acid → ((2-Aminoethyl)thio)acetic acid, methyl ester, hydrochloride

HRID 1283959ノート

反応式

HRID 1283959 の反応式
[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]([OH:8])=[O:7].[CH3:9]OC(OC)(C)C.[ClH:16]>CO>[ClH:16].[CH3:9][O:7][C:6]([CH2:5][S:4][CH2:3][CH2:2][NH2:1])=[O:8]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 64952,2-DimethoxypropaneHCID 4474780HCID 4474780、化合物

生成物 1

HCID 170337((2-Aminoethyl)thio)acetic acid, methyl ester, hydrochloride

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

13.5 g of S-(β-aminoethyl)mercaptoacetic acid and 10.8 g of 2,2-dimethoxy propane are added, successively, to a solution of 7.3 g of gaseous hydrochloride acid in 20 cc of methanol. The solution is permitted to stand for 12 hours at ambient temperature. The flakes formed (17.5 g) are filtered and washed with ethyl acetate. Fusion point = 100°C.

後処理

  1. customThe flakes formed (17.5 g)
  2. filtrationare filtered
  3. washwashed with ethyl acetate
  4. customFusion point = 100°C.

出典と根拠

ORDレコード
ord-d67f649056674ccab262d2f495f48090
出典データセット
uspto-grants-1976_08
特許番号
US03976781

反応ノート

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