alpha-Chloro-o-xylene → 2-Benzyltoluene

HRID 1284267

反応式

HRID 1284267 の反応式
[CH3:1][C:2]1[C:7]([CH2:8]Cl)=[CH:6][CH:5]=[CH:4][CH:3]=1.B(F)(F)F.P(=O)(O)(O)O>C1C=CC=CC=1>[CH2:8]([C:7]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH3:1])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 11093alpha-Chloro-o-xyleneHCID 11480637Phosphoric acid;trifluoroborane

生成物 1

HCID 697382-Benzyltoluene収率 88.4%

試薬・触媒・溶媒 1

HCID 241Benzene溶媒2 回

反応条件

温度
80 °C

実験手順

A solution of 280 parts of o-xylyl chloride in 520 parts of benzene is added to a mixture of 520 parts of benzene and 200 parts of boron fluoride/phosphoric acid (containing 90 parts of boron trifluoride in 110 parts of phosphoric acid) at from 75° to 80°C in the course of one hour. The reaction mixture is stirred for a further three hours at 80°C and allowed to cool, the aqueous solution is separated off and the organic phase is distilled. Yield 322 parts (88.4% of theory) of o-benzyltoluene of boiling point from 145° to 149°C at 17 mm Hg.

後処理

  1. temperatureto cool
  2. customthe aqueous solution is separated off
  3. distillationthe organic phase is distilled

出典と根拠

ORDレコード
ord-feedc8c574ec4b27b60f66be8586943d
出典データセット
uspto-grants-1976_08
特許番号
US03978144

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