Diazoethane → Ethyl 6-methoxymethyloxy-2-naphthyl-alpha-methylacetate

HRID 1284360ノート

反応式

HRID 1284360 の反応式
[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:6]=[C:7]2[C:12](=[CH:13][CH:14]=1)[CH:11]=[C:10]([CH:15]([CH3:19])[C:16]([OH:18])=[O:17])[CH:9]=[CH:8]2.[N+](=[CH:22][CH3:23])=[N-]>C(OCC)C>[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:6]=[C:7]2[C:12](=[CH:13][CH:14]=1)[CH:11]=[C:10]([CH:15]([CH3:19])[C:16]([O:18][CH2:22][CH3:23])=[O:17])[CH:9]=[CH:8]2

参加物

4

反応物 2

HCID 70695DiazoethaneHCID 203350726-Methoxymethyloxy-2-naphthyl-alpha-methylacetic acid

生成物 1

HCID 70589918Ethyl 6-methoxymethyloxy-2-naphthyl-alpha-methylacetate

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒2 回

実験手順

To a solution of 26 g. of 6-methoxymethyloxy-2-naphthyl-α-methylacetic acid and 500 ml. of diethyl ether are slowly added a solution comprising of 5.6 g. of diazoethane and 50 ml. of diethyl ether. The reaction mixture is allowed to stand for 15 minutes and then is evaporated under reduced pressure to yield ethyl 6-methoxymethyloxy-2-naphthyl-α-methylacetate. By replacing diazoethane with diazopropane in the above process, propyl 6-methoxymethyloxy-2-naphthyl-α-methylacetate is obtained.

後処理

  1. customis evaporated under reduced pressure

出典と根拠

ORDレコード
ord-b5559d5436d642d9b0deeafef5534e47
出典データセット
uspto-grants-1976_08
特許番号
US03978116

反応ノート

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