Boron trifluoride → HCID 13588518、化合物

HRID 1284441ノート

反応式

HRID 1284441 の反応式
[C:1]([OH:16])(=[O:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]#[C:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].B(F)(F)F>C(O)(CC)C.CCOCC>[C:1]([O:16][CH:2]([CH2:3][CH3:4])[CH3:1])(=[O:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]#[C:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

参加物

5

反応物 2

HCID 6356Boron trifluorideHCID 53127097-Tetradecynoic acid

生成物 1

HCID 13588518HCID 13588518、化合物収率 170.5%

試薬・触媒・溶媒 2

HCID 3283Diethyl Ether溶媒HCID 6568(+-)-2-Butanol溶媒

実験手順

A solution of 7-tetradecynoic acid (1.22 g) and BF3 -etherate (1 ml) in 20 ml of sec-butyl alcohol was refluxed for 18 hours. The solution was diluted with ether and washed with saturated Na2CO3 solution, water, 2N NaOH, water, and saturated NH4Cl solution. The ether layer was dried (MgSO4) and the solvent removed under reduced pressure to give 1.30 g of sec-butyl 7-tetradecynoate as a yellow liquid.

後処理

  1. washwashed with saturated Na2CO3 solution, water, 2N NaOH, water, and saturated NH4Cl solution
  2. dry with materialThe ether layer was dried (MgSO4)
  3. customthe solvent removed under reduced pressure

出典と根拠

ORDレコード
ord-0ae7ca54a92c4c50b37642c9ed474bc5
出典データセット
uspto-grants-1986_01
特許番号
US04563348

反応ノート

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