Water → 5-(p-Aminophenyl)-1-(p-bromophenyl)-1H-1,2,4-triazole

HRID 128456ノート

反応式

HRID 128456 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][CH:14]=3)=[N:11][CH:10]=[N:9]2)=[CH:4][CH:3]=1.S(S([O-])=O)([O-])=O.[Na+].[Na+].O>CC(C)=O>[NH2:19][C:16]1[CH:17]=[CH:18][C:13]([C:12]2[N:8]([C:5]3[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=3)[N:9]=[CH:10][N:11]=2)=[CH:14][CH:15]=1

参加物

5

反応物 3

HCID 962WaterHCID 24489Sodium DithioniteHCID 12676668HCID 12676668、化合物

生成物 1

HCID 126766735-(p-Aminophenyl)-1-(p-bromophenyl)-1H-1,2,4-triazole

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A mixture of 9.0 g. of 1-(p-bromophenyl)-5-(p-nitrophenyl)-1H-1,2,4-triazole, 18.0 g. of sodium hydrosulfite, 40 ml. of water and 150 ml. of acetone is stirred at room temperature overnight. The acetone is removed in vacuo and the residue is extracted with hot chloroform. Cooling produces 2.1 g. of the desired product as pale yellow crystals, mp. 128°-130° C.

後処理

  1. additionA mixture of 9.0 g
  2. customThe acetone is removed in vacuo
  3. extractionthe residue is extracted with hot chloroform
  4. temperatureCooling
  5. customproduces 2.1 g

出典と根拠

ORDレコード
ord-01176273fad3487795740cd5ce94da69
出典データセット
uspto-grants-1981_03
特許番号
US04259504

反応ノート

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