反応式
C(OC([N:11]1[CH2:15][CH2:14][CH2:13][C@H:12]1[C:16]([NH:18][CH2:19][CH2:20][CH2:21][N:22]1[CH2:26][CH2:25][CH2:24][C:23]1=[O:27])=[O:17])=O)C1C=CC=CC=1>CO.[C].[Pd]>[O:27]=[C:23]1[CH2:24][CH2:25][CH2:26][N:22]1[CH2:21][CH2:20][CH2:19][NH:18][C:16]([C@@H:12]1[CH2:13][CH2:14][CH2:15][NH:11]1)=[O:17]参加物
4
実験手順
In 150 ml of methanol was dissolved 4.32 g of compound (99) and the compound was hydrogenated using 432 mg of 10% palladium-carbon as a catalyst. Then, the catalyst was filtered off from the reaction mixture and the filtrate was concentrated to provide 1.99 g of (S)-N-[3-(2-oxo-1-pyrrolidinyl)propyl]-2-pyrrolidinecarboxamide (100).
後処理
- filtrationThen, the catalyst was filtered off from the reaction mixture
- concentrationthe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-ce61d1d8367c4211bc70a45686c8eb50
- 出典データセット
- uspto-grants-1986_01
- 特許番号
- US04564609
関連ノート
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