Acetic Anhydride → Ethyl 2-butyryl-3-ethoxyacrylate

HRID 128607

反応式

HRID 128607 の反応式
[C:1]([CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])(=[O:5])[CH2:2][CH2:3][CH3:4].[C:12]([O:15][C:16](=O)C)(=O)[CH3:13].C(OC(OCC)OCC)C>>[CH2:12]([O:15][CH:16]=[C:6]([C:1](=[O:5])[CH2:2][CH2:3][CH3:4])[C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH3:13]

参加物

4

反応物 3

HCID 7918Acetic AnhydrideHCID 31214Ethyl orthoformateHCID 238498Ethyl 3-oxohexanoate

生成物 1

HCID 3359484Ethyl 2-butyryl-3-ethoxyacrylate

実験手順

A mixture of ethyl butyrylacetate (105.1 g), acetic anhydride (126 ml) and triethylorthoformate (117 ml) was stirred and boiled under reflux for 1.5 hours. The low boiling materials were distilled off under reduced pressure and the residue distilled under high vacuum to give ethyl 2-(ethoxymethylene)-3-oxohexanoate, b.p. 109°-120° C. (0.4 mmHg).

後処理

  1. temperatureunder reflux for 1.5 hours
  2. distillationThe low boiling materials were distilled off under reduced pressure
  3. distillationthe residue distilled under high vacuum

出典と根拠

ORDレコード
ord-8469f7fe2b9a4676828fda6c5a3ef9f1
出典データセット
uspto-grants-1995_11
特許番号
US05464781

関連ノート

読み込み中…