Acetic Anhydride → Ethyl 2-butyryl-3-ethoxyacrylate
反応式
[C:1]([CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])(=[O:5])[CH2:2][CH2:3][CH3:4].[C:12]([O:15][C:16](=O)C)(=O)[CH3:13].C(OC(OCC)OCC)C>>[CH2:12]([O:15][CH:16]=[C:6]([C:1](=[O:5])[CH2:2][CH2:3][CH3:4])[C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH3:13]参加物
4
実験手順
A mixture of ethyl butyrylacetate (105.1 g), acetic anhydride (126 ml) and triethylorthoformate (117 ml) was stirred and boiled under reflux for 1.5 hours. The low boiling materials were distilled off under reduced pressure and the residue distilled under high vacuum to give ethyl 2-(ethoxymethylene)-3-oxohexanoate, b.p. 109°-120° C. (0.4 mmHg).
後処理
- temperatureunder reflux for 1.5 hours
- distillationThe low boiling materials were distilled off under reduced pressure
- distillationthe residue distilled under high vacuum
出典と根拠
- ORDレコード
- ord-8469f7fe2b9a4676828fda6c5a3ef9f1
- 出典データセット
- uspto-grants-1995_11
- 特許番号
- US05464781
反応ノート
読み込み中…