関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetone | HCID 180 | — |
| 反応物 | Diethyl Ether | HCID 3283 | — |
| 反応物 | 3-Chloropropionic acid | HCID 7899 | — |
| 反応物 | Triphenylphosphine | HCID 11776 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | (2-Carboxyethyl)triphenylphosphonium chloride | HCID 10270534 | — |
反応手順
A mixture of 5.4 g (50 mmol) of 3-chloropropionic acid and 13.1 g (50 mmol) of triphenylphosphine were heated for 2 hours at 145° C. and 2 hours at 95° C. The product, a glassy solid, was dissolved in 200 mL of CHCl3, to which was added 100 mL of Et2O. The volume was reduced to 250 mL. 5 mL of acetone was added to the solution. After 2 hours, 10.98 g of a solid was collected and used immediately in the manner described in Example 29, below.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05464830 |
|---|
| 出典データセット | uspto-grants-1995_11 |
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| ORD ID | ord-10ea3bd5204f49de986abbdae4752b28 |
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| 出典メモ | uspto-grants-1995_11 |
|---|
