化工社化工社 化学情報印刷レポート · 研究参考用
(1,1'-Biphenyl)-4-sulphonyl chloride → N-(4-Methyl-3-trifluoromethyl-5-isoxazolyl)-4-biphenylsulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (1,1'-Biphenyl)-4-sulphonyl chloride | HCID 74192 | — |
| 反応物 | 4-Methyl-3-(trifluoromethyl)isoxazol-5-amine | HCID 15613878 | — |
| 生成物 | N-(4-Methyl-3-trifluoromethyl-5-isoxazolyl)-4-biphenylsulfonamide | HCID 15453174 | 78% |
反応手順
N-(4-Methyl- 3-trifluoromethyl-5-isoxazolyl)-4-biphenylsulfonamide was prepared in the same manner as described in Example 2b from 5-amino-4-methyl-3-trifluoromethyl-isoxazole and 4-biphenylsulfonyl chloride in 78% yield. Purification was achieved by recrystallization from methanol/water to give a white solid, m.p. 139°-140° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05464853 |
| 出典データセット | uspto-grants-1995_11 |
| ORD ID | ord-4c73efb1315242f48afe96f8d56d0ff9 |
| 出典メモ | uspto-grants-1995_11 |