Methanol → N,N-diallyl-O-methylisourea

HRID 1287223ノート

反応式

HRID 1287223 の反応式
[CH2:1]([N:4]([CH2:7][CH:8]=[CH2:9])[C:5]#[N:6])[CH:2]=[CH2:3].[C-]#N.[K+].[CH3:13][OH:14]>O>[CH2:1]([N:4]([CH2:7][CH:8]=[CH2:9])[C:5](=[NH:6])[O:14][CH3:13])[CH:2]=[CH2:3]

参加物

5

反応物 3

HCID 887MethanolHCID 9032Potassium CyanideHCID 10849Cyanamide, diallyl

生成物 1

HCID 21440852N,N-diallyl-O-methylisourea収率 67%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

The following reactants were combined in a 1-liter, round-bottom flask: 24.4 g (0.2 mole) diallylcyanamide, 13 g (0.2 mole) KCN and 500 ml methanol. The mixture was heated under reflux for 24 hours, then stripped in vacuo. The residue was dissolved in 250 ml H2O, which was subsequently extracted with three 200 ml portions of diethyl ether. The organic phases were combined, washed with 200 ml of H2O and dried with MgSO4. The solvent was evaporated to yield 20.7 g (67% yield) of N,N-diallyl-O-methyl isourea.

後処理

  1. temperatureThe mixture was heated
  2. temperatureunder reflux for 24 hours
  3. extractionwhich was subsequently extracted with three 200 ml portions of diethyl ether
  4. washwashed with 200 ml of H2O
  5. dry with materialdried with MgSO4
  6. customThe solvent was evaporated

出典と根拠

ORDレコード
ord-d4fb923db1f44405a42ba48c6b74678f
出典データセット
uspto-grants-1976_10
特許番号
US03984410

反応ノート

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