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4-Hydroxy-3,5-bis(isopropyl)benzaldehyde → 5-[[4-Hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-2-thioxo-4-imidazolidinone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Hydroxy-3,5-bis(isopropyl)benzaldehyde | HCID 82712 | — |
| 反応物 | Sodium Acetate | HCID 517045 | — |
| 反応物 | 2-Thiohydantoin | HCID 1274030 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 5-[[4-Hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-2-thioxo-4-imidazolidinone | HCID 53946215 | 32.9% |
反応手順
Prepared according to the procedure described in Example 1 using 4-hydroxy-3,5-bis(1-methylethyl)benzaldehyde (3.0 g, 15 mmoles), 2-thiohydantoin (1.6 g, 14 mmoles), sodium acetate (4.2 g, 51 mmoles), and acetic acid (35 ml), filtered off, dried, and recrystallized from acetonitrile to afford the pure product (1.4 g), mp 225°-230° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05464856 |
| 出典データセット | uspto-grants-1995_11 |
| ORD ID | ord-94182eba54ee4fcc8316740632dfd6a6 |
| 出典メモ | uspto-grants-1995_11 |