Water → HCID 20322157、化合物

HRID 1287357ノート

反応式

HRID 1287357 の反応式
Cl[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:9][CH2:10][CH2:11][Cl:12].[C:13]([O-:16])(=[O:15])[CH3:14].[Na+].O>C(O)(=O)C>[Cl:12][CH2:11][CH2:10][CH2:9][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[CH2:2][O:16][C:13](=[O:15])[CH3:14]

参加物

5

反応物 3

HCID 962WaterHCID 517045Sodium AcetateHCID 123739901-(Chloromethyl)-2-(3-chloropropyl)benzene

生成物 1

HCID 20322157HCID 20322157、化合物

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

70 g (345 mmols) of 3-(2-Chloromethylphenyl)-propyl chloride (JACS 75, 2053 (1953)) and 50 g (0.61 mmol) of sodium acetate were heated to the boiling point while stirring in 250 ml of glacial acetic acid. It resulted from the thin layer chromatography that the reaction was finished after 41/2 hours. After cooling about 700 ml of water were added and the product was extracted with benzene. The organic phase was washed with water, dried and distilled off after evaporation of the solvent.

後処理

  1. customIt resulted from the thin layer chromatography that the reaction
  2. custom2 hours
  3. additionwere added
  4. extractionthe product was extracted with benzene
  5. washThe organic phase was washed with water
  6. customdried
  7. distillationdistilled off
  8. customafter evaporation of the solvent

出典と根拠

ORDレコード
ord-ef7720a1dc5e4cf2900ce3ad6fe94177
出典データセット
uspto-grants-1976_10
特許番号
US03984459

反応ノート

読み込み中…