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Acetone → HCID 178444015、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetone | HCID 180 | — |
| 反応物 | 2-Chloro-4-methylphenyl isothiocyanate | HCID 143529 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 反応物 | Heptanimidamide hydrochloride | HCID 14144282 | — |
| 溶媒 | Benzene n-pentane | HCID 19707280 | — |
| 生成物 | HCID 178444015 | HCID 178444015 | — |
反応手順
Following a procedure similar to that described in Example 42 and using 2.3 g. sodium in 250 ml. dry acetone, 16.4 g. heptanamidine hydrochloride, and 16 g. 2-chloro-4-methylphenyl isothiocyanate (b.p. 80°-82°C./0.3 mm.; prepared from 2-chloro-4-methylaniline) in 100 ml. dry acetone there was obtained 1-(2-chloro-4-methylphenyl)-3-(heptanimidoyl)-2-thiourea, m.p. 78°-80°C. (from benzene-n-pentane); hydrochloride (23 g.), m.p. 138°-140°C. (from isopropyl alcohol).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03984467 |
| 出典データセット | uspto-grants-1976_10 |
| ORD ID | ord-b0270527fc824ddfa2752b037e6a82c8 |
| 出典メモ | uspto-grants-1976_10 |