1-Methylhydantoin → 5-[[4-Hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-1-methyl-2,4-imidazolidinedione

HRID 128746

反応式

HRID 128746 の反応式
[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:13]([CH3:15])[CH3:14])[C:11]=1[OH:12])[CH:7]=O)([CH3:3])[CH3:2].[CH3:16][N:17]1[CH2:23][C:21](=[O:22])[NH:20][C:18]1=[O:19]>>[OH:12][C:11]1[C:4]([CH:1]([CH3:3])[CH3:2])=[CH:5][C:6]([CH:7]=[C:23]2[N:17]([CH3:16])[C:18](=[O:19])[NH:20][C:21]2=[O:22])=[CH:9][C:10]=1[CH:13]([CH3:15])[CH3:14]

参加物

3

反応物 2

HCID 692171-MethylhydantoinHCID 827124-Hydroxy-3,5-bis(isopropyl)benzaldehyde

生成物 1

HCID 542840515-[[4-Hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-1-methyl-2,4-imidazolidinedione収率 11%

実験手順

Prepared according to the procedure described in Example 92 using 3,5-diisopropyl-4-hydroxybenzaldehyde (2.7 g, 13 mmoles) and 1-methyl hydantoin (1.4 g, 12 mmoles). Recrystallization from acetonitrile gave the pure product (0.4 g), mp 197°-208° C.

後処理

  1. customPrepared
  2. customRecrystallization from acetonitrile

出典と根拠

ORDレコード
ord-5e44d01730fe4f948dd34540ad284fc4
出典データセット
uspto-grants-1995_11
特許番号
US05464856

関連ノート

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