Phenyl isocyanate → HCID 22761475、化合物

HRID 1287675ノート

反応式

HRID 1287675 の反応式
[C:1]1([N:7]=[C:8]=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N:10]1([CH2:16][C:17]2[CH:22]=[C:21]([CH3:23])[CH:20]=[C:19]([CH3:24])[C:18]=2[OH:25])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1>C1C=CC=CC=1>[N:10]1([CH2:16][C:17]2[CH:22]=[C:21]([CH3:23])[CH:20]=[C:19]([CH3:24])[C:18]=2[O:25][C:8](=[O:9])[NH:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1

参加物

4

反応物 2

HCID 7672Phenyl isocyanateHCID 2626172,4-dimethyl-6-(piperidin-1-ylmethyl)phenol

生成物 1

HCID 22761475HCID 22761475、化合物

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

29.75 g (0.25 mol) of phenylisocyanate are introduced dropwise at 0° to 5°C into a solution of 54.75g (0.25 mol) of 2-(piperidinomethyl)-4,6-dimethylphenol in 80 ml of anhydrous benzene. The reaction mixture is stirred at room temperature for 4 hours. The precipitated carbamic acid ester is suction filtered and washed with petroleum ether (b.p. 30°-50°C).

後処理

  1. filtrationfiltered
  2. washwashed with petroleum ether (b.p. 30°-50°C)

出典と根拠

ORDレコード
ord-170914d766674680b392f203dd1a7991
出典データセット
uspto-grants-1976_10
特許番号
US03985789

反応ノート

読み込み中…