Hydrochloric Acid → HCID 86734074、化合物
反応式
[CH3:1][C:2]1[N:3]=[CH:4][S:5][C:6]=1[CH3:7].C1(NC2CCCCC2)CCCCC1.[S:21]1[CH:25]=[CH:24][CH:23]=[C:22]1[C:26]([OH:28])=[O:27].O.Cl>C(OCC)(=O)C>[CH3:1][C:2]1[N:3]=[CH:4][S:5][C:6]=1[CH3:7].[S:21]1[CH:25]=[CH:24][CH:23]=[C:22]1[C:26]([OH:28])=[O:27]参加物
5
実験手順
11.7 g. (0.033 mole) of 4,5-dimethylthiazole-2-thiolcarboxylic acid dicyclohexylamine salt, dissolved in 175 ml. of water and 175 ml. of ethyl acetate, was cooled and acidified with 6N hydrochloric acid to pH 2.2. The layers were separated and the aqueous phase was extracted with 2 × 75 ml. of ethyl acetate. The combined organic phases were dried over magnesium sulfate, filtered and evaporated under reduced pressure yielding 4.6 g. (80%) of a red solid. Infrared spectrum was consistent with the desired material.
後処理
- customThe layers were separated
- extractionthe aqueous phase was extracted with 2 × 75 ml
- dry with materialThe combined organic phases were dried over magnesium sulfate
- filtrationfiltered
- customevaporated under reduced pressure
- customyielding 4.6 g
出典と根拠
- ORDレコード
- ord-364e8ec71fb9429c822e1aa4b9931f3e
- 出典データセット
- uspto-grants-1976_10
- 特許番号
- US03985740
反応ノート
読み込み中…