Sodium ethoxide → HCID 21503525、化合物

HRID 1288169ノート

反応式

HRID 1288169 の反応式
C(OC([N:6]1[CH2:20][CH2:19][C:18]2[C:9](=[N:10][C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=3[C:17]=2[CH3:21])[CH:8](Cl)[CH2:7]1)=O)C.[O-]CC.[Na+]>C(O)C>[CH3:21][C:17]1[C:16]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[N:10]=[C:9]2[CH:8]=[CH:7][NH:6][CH2:20][CH2:19][C:18]=12

参加物

4

反応物 2

HCID 2723922Sodium ethoxideHCID 54025343HCID 54025343、化合物

生成物 1

HCID 21503525HCID 21503525、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 3 gm (5.42 millimols) of 5-chloro-1,2,4,5-tetrahydro-11-methyl-3-azepino[4,5-b]quinoline-carboxylic acid ethyl ester, 45 millimols of sodium ethoxide and 150 ml of ethanol was boiled for 2 hours. After distilling off the ethanol, the residue was dissolved in water, the solution was extracted with chloroform, the extract was dried with sodium sulfate, the solvent was evaporated, and the residue was recrystallized from ether.

後処理

  1. distillationAfter distilling off the ethanol
  2. dissolutionthe residue was dissolved in water
  3. extractionthe solution was extracted with chloroform
  4. dry with materialthe extract was dried with sodium sulfate
  5. customthe solvent was evaporated
  6. customthe residue was recrystallized from ether

出典と根拠

ORDレコード
ord-760affd583a44a6aa0922acbdbf17777
出典データセット
uspto-grants-1976_10
特許番号
US03987047

反応ノート

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