化工社化工社 化学情報印刷レポート · 研究参考用
Trimethylsilyl cyanide → 4-Bromo-2-cyanopyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trimethylsilyl cyanide | HCID 82115 | — |
| 反応物 | 4-Bromopyridin-1-ium-1-olate | HCID 139708 | — |
| 生成物 | 4-Bromo-2-cyanopyridine | HCID 693283 | — |
反応手順
The title compound was prepared from 4-bromopyridine-1-oxide (Rec. Trav. chim., 1951, 70, 581) and trimethylsilyl cyanide, using the procedure described in Chem. Pharm. Bull., 1985, 33, 565, and obtained as a solid (49% yield), m.p. 88°-93° C. Rf 0.53 (SS 11). Found: C,39.15; H,1.50; N,15.07. C6H3BrN2 requires C,39.37; E,1.65; N,15.30%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05750520 |
| 出典データセット | uspto-grants-1998_05 |
| ORD ID | ord-b9e28d64c47c4e2bbcdbe54b64ba0176 |
| 出典メモ | uspto-grants-1998_05 |