Dimethylformamide → HCID 10513597、化合物
反応式
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.CN(C)C=O.[OH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][N:18]=[C:19]=[S:20]>C(Cl)(Cl)Cl.CO>[NH2:1][C:2]1[N:3]([C:19]([NH:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][OH:12])=[S:20])[N:4]=[CH:5][N:6]=1参加物
5
実験手順
The synthesis method of Example 1-(3) was applied. 3-Amino-1H-1,2,4-triazole (4.00 g), dimethylformamide (25 ml) and 5-hydroxypentyl isothiocyanate (9.24 g) were used as reagents. After the reaction, silica gel column chromatography (chloroform-methanol) was applied to give 2.06 g of white crystals (yield 19%). The crystals were subjected to recrystallization from chloroform to give white crystals.
出典と根拠
- ORDレコード
- ord-a324b6d0dd5c453fb78dcb3aa5713fed
- 出典データセット
- uspto-grants-1998_05
- 特許番号
- US05750545
反応ノート
読み込み中…