Methanol, 1,1-diethoxy-, 1-acetate → 6-Methyl[1,2,4]triazolo[1,5-a][1,3,5]triazine-7(6h)-thione

HRID 1289796ノート

反応式

HRID 1289796 の反応式
[NH2:1][C:2]1[N:6]([C:7]([NH:9][CH3:10])=[S:8])[N:5]=[CH:4][N:3]=1.[C:11](OC(OCC)OCC)(=O)C>>[CH3:10][N:9]1[C:7](=[S:8])[N:6]2[N:5]=[CH:4][N:3]=[C:2]2[N:1]=[CH:11]1

参加物

3

反応物 2

HCID 84166Methanol, 1,1-diethoxy-, 1-acetateHCID 32648395-amino-N-methyl-1,2,4-triazole-1-carbothioamide

生成物 1

HCID 2866546-Methyl[1,2,4]triazolo[1,5-a][1,3,5]triazine-7(6h)-thione収率 88%

実験手順

The synthesis method of Example 55 was applied. The compound (1.49 g) obtained in Example 29 and diethoxymethyl acetate (12 ml) were used as reagents. The mixture was reacted at 75° C. for 2 hours to give 1.39 g of white crystals (yield 88%). The crystals were subjected to recrystallization from acetone to give white crystals.

後処理

  1. customThe synthesis method of Example 55
  2. customThe mixture was reacted at 75° C. for 2 hours

出典と根拠

ORDレコード
ord-4146b97b44e04cf2987c623a3440ef5f
出典データセット
uspto-grants-1998_05
特許番号
US05750545

反応ノート

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