Methanol, 1,1-diethoxy-, 1-acetate → HCID 10684276、化合物

反応式

[NH2:1][C:2]1[N:6]([C:7]([NH:9][CH3:10])=[S:8])[N:5]=[C:4]([NH:11][C:12]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[O:13])[N:3]=1.[C:19](OC(OCC)OCC)(=O)C>>[C:12]([NH:11][C:4]1[N:3]=[C:2]2[N:1]=[CH:10][N:9]([CH3:19])[C:7](=[S:8])[N:6]2[N:5]=1)([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[O:13]

参加物

反応物 2

HCID 84166Methanol, 1,1-diethoxy-, 1-acetate

HCID 86752547HCID 86752547、化合物

生成物 1

HCID 10684276HCID 10684276、化合物収率 78%

実験手順

The synthesis method of Example 55 was applied. The compound (551 mg) obtained in Example 35 and diethoxymethyl acetate (8 ml) were used as reagents. The mixture was reacted at 90° C. for 2 hours to give 442 mg of white powdery crystals (yield 78%).

後処理

customThe synthesis method of Example 55
customThe mixture was reacted at 90° C. for 2 hours

出典と根拠

ORDレコード: ord-584e223ed1234dba9eb1c5f259aab9df
出典データセット: uspto-grants-1998_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05750545

反応ノート

読み込み中…

参加物