1-Butanaminium, N,N,N-tributyl-, azide → Ethanethioic acid trans-(+/-)S-[5-(azidomethyl)tetrahydro-3-furanyl]ester
反応式
FC(F)(F)S(O[CH2:7][C@@H:8]1[O:12][CH2:11][C@@H:10]([S:13][C:14](=[O:16])[CH3:15])[CH2:9]1)(=O)=O.[N-:19]=[N+:20]=[N-:21].C([N+](CCCC)(CCCC)CCCC)CCC>C(Cl)Cl>[N:19]([CH2:7][C@@H:8]1[O:12][CH2:11][C@@H:10]([S:13][C:14](=[O:16])[CH3:15])[CH2:9]1)=[N+:20]=[N-:21]参加物
4
反応物 2
生成物 1
試薬・触媒・溶媒 1
実験手順
To a 0° C. solution of 5.768 g of product from Example 22 in 16 ml of methylene chloride, under argon, is added, via syringe, a 0° C. solution of 5.86 g of tetrabutylammonium azide in 16 ml of methylene chloride. The reaction is stirred in an ice bath for 30 minutes and then concentrated in vacuo. The residue is purified by chromatography (Silica Gel: 50% ethyl acetate/hexane) to give 3.418 g of the desired product.
後処理
- concentrationconcentrated in vacuo
- customThe residue is purified by chromatography (Silica Gel: 50% ethyl acetate/hexane)
出典と根拠
- ORDレコード
- ord-d73c3b7ef6c0444da33e3e284a54f9e3
- 出典データセット
- uspto-grants-1998_05
- 特許番号
- US05750735
反応ノート
読み込み中…