Hydrochloric Acid → {2-[4-(Trifluoromethyl)phenyl]hydrazinylidene}acetic acid

HRID 129163

反応式

HRID 129163 の反応式
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:8]=[CH:7][C:6]([NH:9][NH2:10])=[CH:5][CH:4]=1.Cl.O.[C:15]([OH:19])(=[O:18])[CH:16]=O>O>[F:1][C:2]([F:11])([F:12])[C:3]1[CH:4]=[CH:5][C:6]([NH:9][N:10]=[CH:16][C:15]([OH:19])=[O:18])=[CH:7][CH:8]=1

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 1362004-(Trifluoromethyl)phenylhydrazineHCID 15620607Glyoxylic acid, monohydrate

生成物 1

HCID 69587423{2-[4-(Trifluoromethyl)phenyl]hydrazinylidene}acetic acid収率 95%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To a mixture of 5.0 g of 4-(trifluoromethyl)phenylhydrazine (28.4 mmol), 31 ml of water and 3.1 ml of concentrated hydrochloric acid was added 2.9 g of glyoxylic acid-hydrate (31.4 mmol), and the mixture was stirred for one hour at room temperature. The precipitates thus separated out was collected by filtration, washed with water and dried over phosphorus pentoxide to give 6.26 g of 4-(trifluoromethyl)phenylhydrazonoacetic acid (95%) as a pale yellow powder.

後処理

  1. customThe precipitates thus
  2. customseparated out
  3. filtrationwas collected by filtration
  4. washwashed with water
  5. dry with materialdried over phosphorus pentoxide

出典と根拠

ORDレコード
ord-4e10d66f2d2048fa892f7bfb5cdb5d3a
出典データセット
uspto-grants-1995_11
特許番号
US05466820

関連ノート

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