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Methanol → trans-3-[2-(7-Chloroquinolin-2-yl)ethenyl]benzyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Chloroform | HCID 6212 | — |
| 反応物 | trans-3-[2-(7-Chloroquinolin-2-yl)ethenyl]benzyl alcohol | HCID 10827738 | — |
| 溶媒 | Thionyl Chloride | HCID 24386 | — |
| 生成物 | trans-3-[2-(7-Chloroquinolin-2-yl)ethenyl]benzyl chloride | HCID 19369489 | — |
反応手順
To a solution of 813 mg (2.75 mmol) of trans-3-[2-(7-chloroquinolin-2-yl)ethenyl]benzyl alcohol in 40 ml of CHCl3, 1.0 ml of SOCl2 was added, followed by stirring at room temperature for 24 hours. A small amount of MeOH was added to the reaction mixture and the solvent was distilled off under reduced pressure, whereby trans-3-[2-(7-chloroquinolin-2-yl)ethenyl]-benzyl chloride was obtained as pale yellow powder.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05756518 |
| 出典データセット | uspto-grants-1998_05 |
| ORD ID | ord-dd6cbe08df2649148b9b0b3f4e76a229 |
| 出典メモ | uspto-grants-1998_05 |