化工社化工社 化学情報印刷レポート · 研究参考用
Ammonia → HCID 178508172、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | HCID 178478309 | HCID 178478309 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | HCID 178508172 | HCID 178508172 | — |
反応手順
Using the method of Example 6, the product of Example 18, 0.2 g (0.0010 mole) of 4-chloro-1H-imidazo[4,5-c]quinoline was aminated at 175° C. in 12% ammonia in methanol to provide 1H-imidazo[4,5-c]quinolin-4-amine. The structure was verified by comparison of infrared and nuclear magnetic resonance spectra of the product with spectra of the product from Example 23.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05756747 |
| 出典データセット | uspto-grants-1998_05 |
| ORD ID | ord-9c4927f095e64bba899e764604c4df71 |
| 出典メモ | uspto-grants-1998_05 |